Chronic Myeloid Leukaemia

Clinical Features Symptoms of chronic myeloid leukaemia  Onset: insidious. Dragging pain in left hypochondriùm. Gradual swelling of abdomen. Bone pains. Anorexia. Weakness. Palpitation. Dyspnoea. Signs: Anaemia: mild to moderate. Pallor. Sternal tenderness. Splenomegaly: Severe, Non-tender, Hard. Hepatomegaly: mild. Fundoscopy:Leukaemic infiltration, Haemorrhage. Investigations Blood – Hb%: 6-8 g%. – RBC: 2.5 million / Cu mm. – TLC: […]

Chronic Lymphocytic Leukemia

Clinical Features of chronic lymphocytic leukemia Symptoms – Onset: insidious. – Weakness. – Itching. – Anorexia. – Weight loss. – Haemorrhages. Signs: – Painless generalised lymphadenopathy. – Splenomegaly: moderate. – Hepatomegaly: mild. Investigations Blood – TLC: – 50,000 – 250,000 / Cu mm. – Predominantly lymphocytes. Chronic lymphocytic leukemia prognosis – Guarded. Miasmatic Cleavage –  Predominant […]