• GALLBLADDER CANCER (CARCINOMA)

    gallbladder cancer

    Malignant neoplastic growth of gall bladder. Although uncommon, gallbladder cancer is the most common primary hepatobiliary carcinoma (cancer), is the fifth most common malignancy of the gastrointestinal (GI) tract, and predominantly affects older persons with long-standing cholecystolithiasis. Gallbladder epithelial tumors tend to behave similarly to other gastrointestinal (GI) adenocarcinomas. When the diagnosis is made incidentally at the time of cholecystectomy, surgical resection can be curative; however, more commonly, the tumor is unresectable and rarely diagnosed preoperatively despite patients’ symptoms. Early diagnosis can improve the clinical outcome and cure rate of Gallbladder carcinoma.

     

    Causes of GALLBLADDER CANCER

    – Exact cause is not known.
    – Predisposing causes : Chronic calculus cholecystitis, Typhoid carriers.
    – Distribution : Commonest in world.
    – Age: 60-80 years.
    – Sex: common in females.
    – Location
    – Fundus or neck of gall bladder.

     

    CLINICAL FEATURES of GALLBLADDER CANCER

    Bladder Cancer Symptoms

    • Asymptomatic.
    • When symptomatic
        – Onset: insidious.
        – Pain (Right upper abdominal, Continuous, Variable intensity, Worse after eating)
        – Right upper abdominal mass.
        – Anorexia.
        – Fullness after eating.
        – Nausea.
        – Vomiting.
        – Weakness.
        – Malaise.
        – Weight loss.

    Signs
        – Jaundice (obstructive).
        – Anaemia.
        – Gall bladder : Enlarged, Hard, Tender.
        – Liver : Enlarged, nodular around palpable gall bladder.

    COMPLICATIONS of GALLBLADDER CANCER

    – Local extension.
    – Distant metastases.

    INVESTIGATIONS
    USG and CT scan for
        – Diagnosis.
        – Extent of disease.

    PROGNOSIS
        – Poor.
        – Average life span is 6 months or less.

    MIASMATIC CLEAVAGE
        – Mixed miasmatic disorder.

    THERAPEUTIC AIM
        – To evaluate for early surgical intervention.
        – To treat symptomatically.
        – To improve quality of life.

    GENERAL MANAGEMENT
        – Adequate physical, mental rest.
        – Diet : Good nutritious diet, Bland, liquid, soft foods, Small, frequent meals, Avoid fatty foods.

    GALLBLADDER CANCER TREATMENT

    • Arsenicum Album.
    • Calcarea Carbonica.
    • Carcinosin.
    • Carduns Marianus.
    • Chionanthus.
    • Cholesterinum.
    • Conium Mac.
    • Hydrastis Can.
    • Phosphorus.
    • Taraxacum.

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